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Genomic Toxicology
Integration and off-target Site Analysis (ISA) of vectors used in cell and gene therapy
Without reliable primate genomic resources it is difficult to evaluate off-target effects of gene therapies in nonhuman primates
Perform Integration Site Analysis (ISA) of gene therapy vectors in NHP to accurately evaluate the gene therapy vectors
Off-target effects analysis in NHP genomes to better predict the genomic off target effects in human patients
TROOP: Exir Bio primate computational genomics cluster
Using specialized primate computational cluster of Exir Bio (TROOP), our team will help with accurate evaluation of genomic toxicity effects of a drug candidate in primates prior to human clinical trials.
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