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Combine in vitro testing and in silico analysis to optimize preclinical cell and gene therapies

AAV Vectors

Exir Bio provides long-read sequencing to validate AAV constructs used for gene therapy. Once validated, testing on Exir Bio's personalized cells allows researchers to assess potency, functionality and toxicology of AAV vectors prior to testing these therapies in live animals.

Image by CDC
Image by National Cancer Institute

Personalized Cells

Exir Bio provides primates personalized primary cells and stem cells to test gene editing and gene therapies prior to testing them in live monkeys. This platform reduces the use of animals and improves accuracy by using animals' personal genomes to avoid off target effects of gene editing.

Cell Therapy

Autologous and other cell-based immunotherapies are growing for treating human cancers and other diseases. Exir Bio provides immune cells matched with each animal's personal genomes optimization of cell therapies prior to live animal testing, reducing risk and enhancing the reliability of in vitro data.

Image by National Cancer Institute

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